Advancing 3Rs: The Mouse Estrus Detector (MED) as a Low-Stress, Painless, and Efficient Tool for Estrus Determination in Mice.

Int J Mol Sci · 2024 · PMC11395264 · PMID 39273375

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Comparison of the proportion of mice in estrus among females with AR < 6 kOm and AR > 6 kOm ( Figure 5 ) showed highly significant differences in all strains studied: CD-1 (χ 2 = 85.924, df = 1, p < 0.001), FVB/N (χ 2 = 53.539, df = 1, p < 0.001), and C57Bl6/J (χ 2 = 64.744, df = 1, p < 0.001).

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