markedly significantp<0.001
18 Moreover, on clinical examination findings Jilani A et al., found hypotonia (p<0.0017) and early visual impairment (p <0.0001) to be markedly significant in patients with a molecular genetic diagnosis of NCL. 12 We also encountered hypotonia as a significant feature (p<0.001) along with early visual loss (p<0.0001) in patients of genetically proven NCL as compared to the patients with no molecular diagnosis.