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Single-cell EpiChem jointly measures drug-chromatin binding and multimodal epigenome.

Nat Methods · 2024 · PMC11399096 · PMID 39025969

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a decreasing trendno p-value reported
For example, BCL11A, as an oncogene 50 , 51 , displayed a decreasing trend by the transcription factor motif score along pseudotime in Dox-btn for Day3&5, whereas the BCL11A transcription factor score continuously increased in H3K27ac for Day3&5 samples.

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