RNA-modifying enzyme Alkbh8 is involved in mouse embryonic development.

However, after E13.5, the Alkbh8- KO mice ratio showed a decreasing trend and was significantly lower at P28 ( Figure 2 A).

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When comparing Alkbh8 -WT and KO mice in terms of counts per million for each tRNA isoacceptor family, we observed an increasing trend in tRNA-Glu-TTC and tRNA-Arg-TCT, as previously reported ( Figure 3 C).

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