Predictive power of deleterious single amino acid changes to infer on AAV2 and AAV2-13 capsids fitness.

p values less than 0.05 indicate significant multimodality, whereas p values greater than 0.05 but less than 0.10 suggest multimodality with marginal significance. 47 When H 0 for normal distribution was rejected, alternative hypothesis of multimodality was validated by LaplacesDemon package’s functions in R.

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