The role of <i>Rhizoma Paridis</i> saponins on anti-cancer: The potential mechanism and molecular targets.

Heliyon · 2024 · PMC11407946 · PMID 39296108

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a decreasing trendno p-value reported

Results showed that polyphyllin I led to a dose-dependent increase in the expression of LC3-II in HGC-27 cells, while the expression of p62 showed a decreasing trend.

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an increasing trendno p-value reported

The apoptosis-promoting elements consisting of Bax, cytochrome c in the cytoplasm, activated caspase-3, and activated caspase-9 showed an increasing trend in human ovarian cancer cells (SKOV3) after the treatment of polyphyllin II.

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