There is an overall trend that heterochromatin-related genes have larger dN/dS ratios than the Polycomb control genes (medians = 0.0974 [heterochromatin-related genes] vs. 0.0852 [Polycomb controls]) and random genes (medians = 0.0802), and this difference is statistically significant for comparisons to random genes (Mann–Whitney U test, P = 0.167 [compared to Polycomb control] and 0.0032 [compared to random genes]).
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