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Combined KRAS and TP53 mutation in patients with colorectal cancer enhance chemoresistance to promote postoperative recurrence and metastasis.

BMC Cancer · 2024 · PMC11409552 · PMID 39289671

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a notable trendno p-value reported
Our study has indeed revealed a notable trend where patients harboring combined mutations in TP53 and KRAS genes exhibit a higher likelihood of relapse following surgical intervention.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.