Δ H° values show an increasing trend, suggesting that dissolution of NAP at higher concentrations of 2-PrOH becomes more endothermic. Δ S° values also increase, indicating a higher level of disorderliness during dissolution.
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Solubility determination, mathematical modeling, and thermodynamic analysis of naproxen in binary solvent mixtures of (1-propanol/2-propanol) and ethylene glycol at different temperatures.
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