Inflammaging represents a highly significant risk factor for the development of neurodegenerative diseases including Alzheimer’s and Parkinson’s, which are characterized by progressive degeneration of neurons in the brain and peripheral nervous system, and they are additionally accompanied by immune system dysfunction ( 22 , 29 ).
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Immune system dysfunction and inflammation in aging <i>Shank3b</i> mutant mice, a model of autism spectrum disorder.
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