Mitochondrial metabolism blockade nanoadjuvant reversed immune-resistance microenvironment to sensitize albumin-bound paclitaxel-based chemo-immunotherapy.

∗∗ P < 0.01 and ∗∗∗ P < 0.001 were extremely significant. ns, no significant difference, P > 0.05. 3 Results and discussion 3.1 TPP-TAM inhibited PD-L1 and TGF-β expression in 4T1 cells For the past few years, TAM has been widely used as adjuvant therapy for the endocrine treatment of a variety of breast cancers 30 , 31 .

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