Notably, under the HF/HS diet, KO mice showed an increasing trend in nighttime oxygen consumption and both daytime and nighttime energy expenditure, suggesting that KO mice may have higher energy expenditure than WT mice ( Fig. 4 I, J) without notable differences in energy intake or physical activity ( Fig. 4 K).
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Natriuretic peptide receptor-C perturbs mitochondrial respiration in white adipose tissue.
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