A recent randomized trial that included 567 participants demonstrated that there was marginally significant difference between infection rates of 0% (0/287) after transperineal biopsy without prophylactic antibiotics and 1.4% (4/280) after that with prophylactic antibiotics ( P = .059) [ 13 ].
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CT-guided transperineal biopsy for prostate cancer in the absence of rectal access.
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