Barely Significant
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Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms.

PLoS One · 2024 · PMC11421771 · PMID 39316592

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highly significantp <0.00005actually significant
When exposing 104C1 cells that acquire a fibroblast morphology to increasing concentrations of KDC203, we observed highly significant ( p <0.00005) dose-dependent reductions in PrP C levels ( Fig 2A ).

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