Effect of Mediterranean diet on body mass index and fatigue severity in patients with multiple sclerosis: A systematic review and meta-analysis of clinical trials.

MeD and MFIS While a decreasing trend in fatigue severity was observed, the pooled estimate did not indicate a significant enhancement in MFIS scores among patients adhering to the MeD (WMD = −8.29; 95 % CI = −16.74, 0.16; P = 0.054), as analyzed across three RCTs involving 249 participants [ 3 , 19 , 21 ].

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