Notable highly significant DEGs were related to development and cartilage metabolism, with the downregulation of structural PCM and ECM proteins, such as COL27A1 and PRG4 , increased catabolic activity, such as MMP9 , and ECM mineralization, such as SPP1 (Figure 3A,B ).
← all excerpts
A Damaging COL6A3 Variant Alters the MIR31HG-Regulated Response of Chondrocytes in Neocartilage Organoids to Hyperphysiologic Mechanical Loading.
1
—
—