The design of CDs for practically significant solubility is accomplished by endowing them with appropriate surface groups; the introduction of hydrophilic moieties, such as hydroxyls, amines, or carboxyls, results in high solubility in hydrophilic solvents, [ 18 , 215 ] while the addition of hydrophobic groups, such as alkyls and epoxy groups, is concomitant with a high solubility in hydrophobic solvents.
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