Contrasting Dynamics of Intracellular and Extracellular Antibiotic Resistance Genes in Response to Nutrient Variations in Aquatic Environments.

By contrast, the eARGs in water showed an increasing trend with the increase of the dosing frequency, and the highest eARG abundance was found under the high-frequency dosing regimen (20 times/10 d), which was 1.35–1.43 times higher than that of lower frequency dosing.

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Conversely, the relative abundance of eARGs in water showed a decreasing trend, consistent with the microcosm result.

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