In another case, Hirata and colleagues presented a decreasing trend in uterine volume (from 285.4 cm 3 to 259.8 cm 3 ) in adenomyosis patients treated with dienogest for 24 weeks, although the difference was statistically insignificant [ 25 ].
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Clinical efficacy of dienogest against endometriomas with a maximum diameter of ≥4 cm.
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