marginally significantP = 0.06
The inverse trend across categories of childhood body fatness was somewhat more apparent among those who were heavy than among those who were lean at age 18 years, and the test for interaction was marginally significant (χ 2 1 = 3.68; P = 0.06), although the multivariate RRs for the most overweight compared with the most lean in childhood were very similar in both categories of BMI at age 18 years (RR = 0.42 among those with BMI <22 kg/m 2 at age 18 years, P for trend = 0.08; and RR = 0.49 among those with BMI ≥ 22 kg/m 2 at age 18 years, P for trend = 0.001).