Effects of GBT1118, a voxelotor analog, on bone disease in sickle cell disease mice.

Sci Rep · 2024 · PMC11436716 · PMID 39333172

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highly significantno p-value reported

In the present study histomorphometry demonstrated significantly increased osteoclast number and activity and GBT1118 mediated reduction in osteoclast numbers and activity in SCD mice of both sexes is highly significant.

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