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Impact of pneumococcal conjugate vaccines on invasive pneumococcal disease-causing lineages among South African children.

Nat Commun · 2024 · PMC11436952 · PMID 39333488

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a decreasing trendno p-value reported
Although the effective population sizes for GPSC9 (serotype 14 and 15A) and GPSC10 (serotype 14, serogroup 24) showed similar increases around the 1990s, a decreasing trend in the effective population size for GPSC9 was observed before the introduction of PCV7 followed by a slight increase after PCV13 introduction (Fig. 3b ).

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