Real-world outcomes of patients with hereditary angioedema with normal C1-inhibitor function and patients with idiopathic angioedema of unknown etiology in Canada.

Similarly, a decreasing trend in the duration and number of angioedema attacks before and after HAE treatment initiation was observed for patients with AE-UNK; however, these results were not significant.

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These data taken together with the diagnostic delay indicates a highly significant burden of disease in untreated patients.

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