7 Trials with other pulmonary vasodilator therapies including endothelin receptor antagonists and inhaled prostacyclin analogs, demonstrate similar findings with an overall trend toward improved exercise performance that is not uniform across Fontan patient phenotypes. 4 , 5 , 6 Low cerebral blood flow and oxygen delivery contribute to structural and functional abnormalities in the Fontan brain.
← all excerpts
Exercise Performance: A Fontan Phenotype Predictive of Long-Term Survival.
1
—
—