Barely Significant
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The triglyceride-glucose index dynamic trajectory reveals the association between the clinical subphenotype of insulin resistance and mortality in patients with sepsis.

BMC Infect Dis · 2024 · PMC11443761 · PMID 39354398

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a decreasing trendno p-value reported
However, when it comes to different individuals within the same subphenotype, for instance, the patients in IR decreasing subphenotype both exhibiting a decreasing trend in TyG index, we cannot fully quantify whether a decline from higher value to middle range is superior, inferior or equivalent to a decline from middle range to an even lower value.

also in 47,180 other papers

an increasing trendno p-value reported
In the stratified analysis, we observed that patients over 60 years old, without hypertension, heart failure, CAD, or T2DM had a higher risk of mortality when exhibiting an increasing trend in IR.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.