Synovial vancomycin and meropenem concentrations in periprosthetic joint infection treated by single-stage revision combined with intra-articular infusion.

A considerable reduction in synovial fluid leucocyte count was noted (p < 0.001 total, Wilcoxon signed-rank test), with a trend towards significance in the hip (p < 0.001, Wilcoxon signed-rank test) and clear importance in the knee (p = 0.008, Wilcoxon signed-rank test).

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