Maintaining mitochondrial DNA copy number mitigates ROS-induced oocyte decline and female reproductive aging.

The quantification data exhibited a decreasing trend in SDHB, while the other complex subunits, as well as the total mitochondrial mass indicated by TOMM20 protein levels, were unaffected (Fig.

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There was an increasing trend in ATP levels in NMN-treated L/L, M; Cre oocytes compared to their PBS group, while NMN-treatment did not increase ATP levels in control oocytes compared to their PBS group (Fig. 7f ).

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