Furthermore, we also found that ABCG2 activity after bariatric surgery is closely related to the AMPK/Nrf2 pathway, and the development of novel drugs based on this pathway may be significant for regulating urate excretion and thus improving HN.
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Sleeve gastrectomy ameliorates renal injury in obesity-combined hyperuricemic nephropathy mice by modulating the AMPK/Nrf2/ABCG2 pathway.
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