In cases of high flow, that is, with minimal diffuse coronary atherosclerosis or microvascular dysfunction, the trans-stenotic gradient may be significant and ≤0.80, yet the maximum achievable flow may still suffice to avoid myocardial ischaemia.
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Dobutamine stress echocardiography after positive CCTA: diagnostic performance using fractional flow reserve and instantaneous wave-free ratio as reference standards.
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