High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer's disease.

Similarly, a positive correlation between scAb affinities and B 50 values measuring dGAE-dGA binding inhibition was observed for the tau-tau immunoassay, however did not quite reach statistical significance (Fig. 5 D) ( R = 0.575, P = 0.0504).

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