Additionally, a decreasing trend in fucosylation, along with an increase in endogenous O‐glycosylation, may contribute to the progression of AD. 141 Additionally, Shi et al. 142 developed a targeted MS approach utilizing multifragmentation techniques for the identification of O‐glycosites.
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However, recent statistics indicate a worrying trend: an increase in the incidence of CRC among younger populations. 250 , 251 , 252 In response, the medical community has expanded its arsenal beyond traditional treatments such as surgery, chemotherapy, and radiotherapy.