The greatest impact of adipose-derived MCP-1 apparently was on amino acid metabolism because of the highly significant alterations in the aminoacyl-tRNA-biosynthesis and the phenylalanine, tyrosine and tryptophan biosynthesis pathways in Mcp-1 -/- mice.
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Metabolomic Alteration in Adipose Monocyte Chemotactic Protein-1 Deficient Mice Fed a High-Fat Diet.
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