Within the 2 adjuvant RCTs, the adjuvant ICI group demonstrated a significant benefit in DFS (HR = 0.78, 95% CI: 0.69–0.90) and a nonsignificant trend toward improved OS (HR = 0.94, 95% CI: 0.78–1.12) compared to the control group ( Figure 2(b) and ( c )).
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Efficacy and safety of perioperative, neoadjuvant, or adjuvant immunotherapy alone or in combination with chemotherapy in early-stage non-small cell lung cancer: a systematic review and meta-analysis of randomized clinical trials.
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