Eosinophilic esophagitis and inhalant antigens: Pointing out the roles of allergic rhinitis, immunotherapy and biologic treatment.

5 Compared to EoE, the prevalence of AR is much higher, reported from 5% to 50% worldwide, with an increasing trend with age until young adulthood. 6 EoE is a chronic non-IgE-mediated disease, driven by food and environmental antigens stimulating a type 2 immune response, resulting in inflammation, remodeling and motility dysfunction of the esophagus. 5 Clinical manifestations may differ according to the age.

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