In this study, 4 SNP sites were identified in the regulatory region of the seventh exon of DKK3 in chickens, among which the g.8419598 (C > T) site showed a highly significant correlation with abdominal fat weight and abdominal fat percentage in KwangFeng Ma chicken.
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DKK3 promotes adipogenic differentiation of stem cells by inhibiting Wnt/β-catenin signaling pathway related gene expression and mitochondrial autophagy function.
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