SAL0114: a novel deuterated dextromethorphan-bupropion combination with improved antidepressant efficacy and safety profile.

Front Pharmacol · 2024 · PMC11462627 · PMID 39386030

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extremely significantno p-value reported

Meanwhile, the high dose of deDM + BUP (18 mg/kg+50 mg/kg) not only had a significant difference with deDM but also had a significant difference with the BUP group, and it was extremely significant, which also reflected the synergistic effect of BUP and deDM.

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