Drug Repurposing Using Molecular Network Analysis Identifies Jak as Targetable Driver in Necrobiosis Lipoidica.

Fisher’s exact test demonstrated highly significant enrichment of current FDA-approved psoriasis biologics at both D1 ( Figure 2 d) and D2 (data not shown) ( GSE54456 : P = 1.42E-15 and 9.62E-7, respectively; GSE121212 : P = 5.13E-12 and 1.56E-6, respectively).

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