[ 34 ] The changes that resulted from the hydrogel‐targeted of BMDM capture were further explored using flow cytometry, with results showing that after cointervention with lipopolysaccharide (LPS) (100 ng mL −1 ) to stimulate an inflammatory environment, the proportion of CD86 + /CD11b + cells was higher and CD206 + /CD11b + cells lower after 3 d ( Figure 3 A–C ), while the proportion of CD86 + /CD11b + cells showed a decreasing trend and the proportion of CD206 + /CD11b + cells showed an increasing trend after 7 d (Figure 3D–F ).
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Ligand-Selective Targeting of Macrophage Hydrogel Elicits Bone Immune-Stem Cell Endogenous Self-Healing Program to Promote Bone Regeneration.
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