We observed an increasing trend of IL-9 + Th cells (both percentage and mean fluorescence intensity-MFI) in the BM of Ovx mice at day 15 post-Ovx, which was significantly enhanced at days 30 and 45 ( Figure 1M ) ( Figure S3A-G ).
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Targeting the osteoclastogenic cytokine IL-9 as a novel immunotherapeutic strategy in mitigating inflammatory bone loss in post-menopausal osteoporosis.
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