Respiratory pathology in the TDP-43 transgenic mouse model of amyotrophic lateral sclerosis.

Front Physiol · 2024 · PMC11471906 · PMID 39403566

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a decreasing trendno p-value reported

The 4-week male TDP-43 A315T mice showed a decreasing trend in minute ventilation (MV), tidal volume (TV), peak inspiratory flow (PIF), and peak expiratory flow (PEF), and significantly reduced inspiratory flow rate (TV/Ti) compared to age-matched WT mice.

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