Virus-like particles as robust tools for functional assessment: Deciphering the pathogenicity of ABCA4 genetic variants of uncertain significance.

J Biol Chem · 2024 · PMC11474199 · PMID 39222682

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highly significantno p-value reported

The phenotypic impact of a misfolding variant can be highly significant since the protein never reaches its required cellular destination ( 87 ).

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