Immunohistochemical Expression of Caspase1 and Epidermal Growth Factor Receptor in Invasive Breast Carcinoma and Their Biological and Prognostic Associations.

There was a highly significant statistical difference between combined expression groups (p≤0.001), as Caspase1 -positive/ EGFR -low-expression pattern was associated with longest OS (64.7months), while Caspase-negative/ EGFR overexpression pattern was associated with the shortest OS (24.6 months) among the 4 combined expression groups as demonstrated by the Kaplan-Meier curve for OS ( Figure 3 ).

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