Galectin 3-binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis.

Cancer Commun (Lond) · 2024 · PMC11483554 · PMID 39073023

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an unexpected trendno p-value reported

Interaction of LGALS3BP with ITGαV and promotion of ITGαV accumulation on the cell membrane to release TGF‐β1 We observed an unexpected trend in TGFB1 mRNA expression and the amount of secreted total TGF‐β1 in the culture medium upon rLGALS3BP treatment.

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