Cyp7a1 had a decreasing trend in the MF and MSI‐1436‐treated male and female livers relative to CTL male and female livers, respectively, with multi‐factor ANOVA indicating an overall significant effect due to treatment ( p = 0.016) (Figure S1c ).
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Early life interventions metformin and trodusquemine metabolically reprogram the developing mouse liver through transcriptomic alterations.
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