Zhi-Kang-Yin formula attenuates high-fat diet-induced metabolic disorders through modulating gut microbiota-bile acids axis in mice.

Consistent with previous results, the relative proportion of non-12-OH bile acids in the ZKY group showed an increasing trend after 48 h (Fig. 7 C).

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In both BA profiles, UDCA species and CA species showed a decreasing trend in Con group compared to HFD group but increased in ZKY group compared to HFD group, while the LCA species demonstrated an opposite trend.

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