Other investigations conducted in diverse geographical areas have also showed a decreasing trend of S. mansoni infection prevalence. 37 , 38 , 39 , 40 , 41 Factors likely to contribute to this decline appear to include: (1) expanded access to MDA programs and preventive chemotherapy, leading to reduced prevalence and infection intensity, seen, for example, in East and West Africa 42 , 43 , 44 ; (2) improvement in water, sanitation and hygiene (WASH), 45 leading to decreased transmission; (3) enhanced health education to raise awareness and prevent transmission; and (4) targeted control campaigns in high-prevalence areas to reduce disease.
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Prevalence of human <i>Schistosoma mansoni</i> infection in endemic regions (2010-2024): a systematic review and meta-analysis.
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