TBK1 adaptor AZI2/NAP1 regulates NDP52-driven mitochondrial autophagy.

In AZI2-TBKBP1 DKO cells, a minor reduction in the mitophagy flux was observed with a marginally significant difference relative to WT cells observed in clone #12 but not clone #20 ( Fig. 3 , B and C ).

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TBK1 levels in one of the TKO clones was similarly impacted, albeit with marginal significance relative to WT.

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