Evaluation of miRNA-27a/b expression in patients with familial hypercholesterolemia.

Arch Med Sci · 2024 · PMC11493071 · PMID 39439685

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0590

boldest claim

The sentences

borderline significantp = 0.054so close (0.05 < p ≤ 0.1)

In the regression analysis, FH zygosity was a significant determinant of miRNA-27 levels in the crude regression model ( p = 0.039), while it had a borderline significant effect on miRNA-27 levels in the age-adjusted model ( p = 0.054).

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of borderline significancep = 0.059so close (0.05 < p ≤ 0.1)

However, in comparing HeFH patients and healthy individuals, the difference in expression level was of borderline significance (fold change: 1.62 ±0.46, p = 0.059).

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