an increasing trendp < 0.001
hrHPV infection (adjusted [aOR] = 4.08, 95% CI: 3.00–5.54), HPV16 infection (aOR = 4.71, 95% CI: 3.39–6.53), HPV58 infection (aOR = 2.29, 95% CI: 1.41–3.73) and PAHs high exposure (aOR = 2.57, 95% CI: 1.82–3.62) increased the risk of CIN2/3, showing an increasing trend ( p < 0.001) with the severity of cervical lesions ( 39 ). 1.1.9 Others There is increasing evidence that chronic inflammation is involved in carcinogenesis and cancer progression.