Although this difference was not statistically significant, it represents an interesting trend because this cell loss was much more profound in the DR case, in which approximately 60% of both interneuron types were lost compared with that in control eyes (PV plus cells: 3.63 ± 1.07 vs. 1.36 ± 0.84; PKCα plus cells: 4.75 ± 1.39 vs. 1.97 ± 1.09; P < 0.0001 for both) ( Fig. 6 D and F ).
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Deciphering the Connection Between Microvascular Damage and Neurodegeneration in Early Diabetic Retinopathy.
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